The Opening Plenary facilitated at the 2025 Mechanical Support and Thoracic Transplantation Summit features international experts exploring advancements shaping the future of thoracic transplantation, from AI-driven decision-making to novel clinical approaches and program strategy. Featured presentations include:

• Welcoming Remarks
• How Can AI Help in Donor Organ Selection — Dr. Shaf Keshavjee
• How Can AI Help in Recipient Selection/Allocation — Dr. William Parker
• How to Lose Money in Thoracic Transplant Without Even Trying — Brigitte Sullivan
• The Spanish Approach for Maximizing Thoracic Transplantation in DCDs — Dr. Eduardo Miñambres
• Mitochondrial Transplants for Heart and Lungs — Dr. James McCully